PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2012 | 61 | 1 |
Tytuł artykułu

Prevalence of class 1 integron among multidrug-resistant Acinetobacter baumannii in Tabriz, northwest of Iran

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Integrons are associated with a variety of gene cassettes, which confer resistance to multiple classes of antibacterial drugs. In this study we tested the frequency of class 1 and 2 integrons among multidrug-resistant Acinetobacter baumannii (MDRAB) clinical isolates. One hundred clinical isolates of A. baumannii were screened for carriage of class 1 and 2 integrons by PCR method. Results showed that seventy four (92.5%) of 80 MDRAB carried class 1 integron. Integron-positive isolates were statistically more resistant to aminoglycoside, quinolone and beta-lactam compounds except for cefepime. This is the first report of class 1 integrons in MDRAB isolates in northwest Iran.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
61
Numer
1
Opis fizyczny
p.57-60,fig.,ref.
Twórcy
autor
  • Department of Microbiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
autor
autor
autor
autor
autor
autor
Bibliografia
  • Berlau J., H.M. Aucken, H. Malnick and T.L. Pitt. 1999. Distribution of Acinetobacter spp. on skin of healthy humans. Eur. J. Clin. Microbiol. Infect. Dis. 18: 179–183.
  • Clinical and Laboratory Standard Institute. 2006. Performance standards for antimicrobial disk susceptibility tests. Approved standard M2-A9. Wayne, PA: CLSI
  • Dijkshoorn L., A. Nemec and H. Seifert. 2007. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat. Rev. Microbiol. 5: 939–951.
  • Dinc U., G. Bayramoglu, K. Buruk, H. Ulusoy, I. Tosun and N. Kaklikkaya. 2010. Molecular epidemiology of Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolated from clinical specimens at an intensive care unit. Saudi. Med. J. 31: 453–455.
  • Feizabadi MM., B. Fatollahzadeh, M. Taherikalani, M. Rasoolinejad, N. Sadeghifard, M. Aligholi, S. Soroush and S. Mohammadi- Yegane. 2008. Antimicrobial susceptibility patterns and distribution of blaOXA genes among Acinetobacter spp. Isolated from patients at Tehran hospitals. Jpn. J. Infect. Dis. 61: 274–278.
  • Gu B., M. Tong, W. Zhao, G. Liu, M. Ning, S. Pan and W. Zhao. 2007. Prevalence and characterization of class I integrons among Pseudomonas aeruginosa and Acinetobacter baumannii isolates from patients in Nanjing, China. J. Clin. Microbiol. 45: 241–243.
  • Huang L.Y., T.L. Chen, P.L. Lu, C.A. Tsai, W.L. Cho, F.Y. Chang, C.P. Fung and L.K. Siu. 2008. Dissemination of multidrug-resistant, class 1 integron-carrying Acinetobacter baumannii isolates in Taiwan. Clin. Microbiol. Infect. 14: 1010–1019.
  • Liu S.Y., J.Y. Lin, C. Chu, S.u. LH, T.Y. Lin and C.H. Chiu. 2006. Integron-associated imipenem resistance in Acinetobacter baumannii isolated from a regional hospital in Taiwan. Int. J. Antimicrob. Agents. 27: 81–84.
  • Marais E., G. de. Jung, V. Ferraz, B. Maloba and A.G. Dusé. 2004. Interhospital transfer of pan-resistant Acinetobacter strains in Johannesburg, South Africa. Am. J. Infect. Control. 32: 278–281.
  • Martinez-Freijo P., A.C. Fluit, F.J. Schmitz, V.S. Grek, J. Verhoef and M.E. Jones. 1998. Class I integrons in Gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds. J. Antimicrob. Chemother. 42: 689–696
  • Merkier A.K., M. Catalano, M.S. Ramírez, C. Quiroga, B. Orman, L. Ratier, A. Famiglietti, C. Vay, A. Di Martino, S. Kaufman and D. Centrón. 2008. Polyclonal spread of bla(OXA-23) and bla(OXA-58) in Acinetobacter baumannii isolates from Argentina. J. Infect. Dev. Ctries. 2: 235–240.
  • Nemec A., L. Dolzani, S. Brisse, P. Van den Broek and L. Dijk-shoorn. 2004. Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones. J. Med. Microbiol. 53: 1233–1240.
  • Oh J.Y., K.S. Kim, Y.W. Jeong, J.W. Cho, J.C. Park and J.C. Lee. 2002. Epidemiological typing and prevalence of integrons in multiresistant Acinetobacter strains. APMIS. 110: 247–252.
  • Peleg A.Y., H. Seifert, D.L. Paterson. 2008. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 21: 538–582.
  • Perez F., A.M. Hujer, K.M. Hujer, B.K. Decker, P.N. Rather and R.A. Bonomo. 2007. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob. Agents. Chemother. 51: 3471–3484.
  • Shibata N., Y. Doi, K. Yamane, T. Yagi, H. Kurokawa, K. Shibayama, H. Kato, K. Kai and Y. Arakawa. 2003. PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integron. J. Clin. Microbiol. 41: 5407–5413.
  • Turton J.F., M.E. Kaufmann, J. Glover, J.M. Coelho, M. Warner, R. Pike, T.L. Pitt. 2005. Detection and typing of integrons in epidemic strains of Acinetobacter baumannii found in the United Kingdom. J. Clin. Microbiol. 43: 3074–3082.
  • Turton J.F., N. Woodford, J. Glover, S. Yarde, M.E. Kaufmann and T.L. Pitt. 2006. Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J. Clin. Microbiol. 44: 2974–2976.
  • Vila J., S. Martí and J. Sánchez-Céspedes. 2007. Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii. J. Antimicrob. Chemother. 59: 1210–1215.
Uwagi
PL
Rekord w opracowaniu
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-19ac2441-3279-40bb-b472-49a0da5cd991
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.