Kliniczne i anatomiczne uwarunkowania chorób degeneracyjnych centralnego układu nerwowego u psów i kotów

• Autorzy: Luszczewska-Sierakowska I. , Lada A.

Warianty tytułu

EN

Clinical and anatomical conditioning of degenerative diseases of the central nervous system in animals

• Języki publikacji: PL

Abstrakty

EN

Because of its special function in the body, diseases of the central nervous system can be very dramatic, especially if they affect the centres controlling the most vital functions of the body. They can develop as primary diseases or as secondary diseases, i.e. complications of another disease, the focus of which is located outside the nervous system. Diseases of the nervous system may affect its peripheral part (inflammation of nerves, polyneuropathies, radicular syndrome) or its central part (neuroinfections, developmental anomalies, dementia, trauma, tumors, epilepsy, stroke). There are also neurological diseases causing simultaneous changes to the peripheral and central parts. They are demyelination diseases, such as multiple sclerosis and transverse myelitis. There are also diseases affecting the spinal cord selectively. Muscle diseases such as myasthenia and muscular dystrophy, in which disorders of neuromuscular transmission are observed, may also be considered as neurological diseases. There is also a group of neurological diseases in which mental disorders can occur. Such diseases include, most importantly, dementia (Alzheimer’s disease, dementia with Levy bodies, fronto-temporal dementia) and encephalopathies (metabolic, traumatic, ischemic). During later stages of a neurological disease, mental symptoms resulting directly from numerous injuries to the central nervous system may occur. Neurodegenerative diseases in domestic animals are quite rare. However, they represent a very important and very large group of diseases. Many of these degenerations are similar to diseases occurring in humans, which makes it possible to understand them better by carrying out research on animals. Unfortunately, in many cases all we know about these diseases are their clinical symptoms, pathological changes that occur in their course and conclusions drawn from genealogical examinations. The introduction of more recent examination methods and new instruments makes it possible to obtain increasingly detailed knowledge of these diseases on the molecular level and, above all, a better understanding of their causes. Neurodegenerative disorders are among the most life-altering diseases and are therefore very costly to society.

Słowa kluczowe

PL

psy; koty; uklad nerwowy osrodkowy; choroby ukladu nerwowego; choroby neurodegeneracyjne; uwarunkowania; przyczyny; objawy chorobowe

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2012
• Tom: 68
• Numer: 04
• Opis fizyczny: s.199-204,bibliogr.

Twórcy

autor

Luszczewska-Sierakowska I.

• Zakład Anatomii Zwierząt, Katedra Anatomii i Histologii Zwierzat, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Akademicka 12, 20-950 Lublin

autor

Lada A.

Bibliografia

• 1.Bennett P. F., Clarke R. E.: Laryngeal paralysis in a Rottweiler with neuroaxonal dystrophy. Aust. Vet. J. 1997, 75, 784-786.
• 2.Berg B. O., Rosenberg S. H., Asbury A. K.: Giant amonal neuropathy. Pediatrics 1972, 49, 894-899.
• 3.Berghaus R. D., O'Brien D. P., Thorne J. G., Buening G. M.: Incidence of canine dysautonomia in Missouri, USA, between January 1996 and December 2000. Prev. Vet. Med. 2002, 54, 291-300.
• 4.Bildfeld R. J., Mitchell S. K., De Lahunta A.: Cerebellar cortical degeneration in a Labrador retriever. Can. Vet. J. 1995, 36, 570-572.
• 5.Björck G., Dyrendahl S., Olsson S.-E.: Hereditary ataxia in smooth-haired Fox Terriers. Vet. Rec. 1957, 69, 871-876.
• 6.Braund K. G.: Degenerative disorders of the Central Nervous System, [w:] Braund K. G. (Ed): Clinical Neurology in Small Animals - Localization, Diagnosis and Treatment. International Veterinary Information Service, Ithaca, NY 2003.
• 7.Braund K. G., Vandevelde M.: German shepherd dog myelopathy - a morphologic and morphometric study. Am. J. Vet. Res. 1978, 39, 1309-1315.
• 8.Carmichael K. P., Miller M., Rawlings C. A., Fischer A., Oliver J. E., Miller B. E.: Clinical, hematologic, and biochemical features of a syndrome in Bernese Mountain Dogs characterized by hepatocerebellar degeneration. JAVMA 1996, 208, 1277-1279.
• 9.Coates J. R., O’Brien P., Kline K. L., Storts R. W., Johnson G. C., Shelton G. D., Petterson E. E., Abbott L. C.: Neonatal cerebellar ataxia in Coton de Tulear dogs. J. Vet. Intern. Med. 2002, 16, 680-689.
• 10.Cottrell D. F., McGorum B. C., Pearson G. T.: The neurology and enterology of equine grass sickness: a review of basic mechanisms. Neurogastroenterol. Motil. 1999, 11, 79-92.
• 11.Cummings J. F., De Lahunta A.: A study of cerebellar and cerebral cortical degeneration in miniature poodle pups with emphasis on the ultrastructure of Purkinje cell changes. Acta Neuropathol. 1988, 75, 61-71.
• 12.Lahunta A. De: Abiotrophy in domestic animals: a review. Can. J. Vet. Res. 1990, 54, 65-76.
• 13.Lahunta A. De, Averill D. R.: Hereditary cerebellar cortical and extrapyramidal nuclear abiotrophy in Kerry Blue Terriers. JAVMA 1976, 168, 1119-1124.
• 14.Leon G. De., Mitchell M. H.: Histological and ultrastructural features of dystrophic isocortical axons in infantile neuroaxonal dystrophy (Seitelberger's disease). Acta Neuropathol. 1985, 66, 89-97.
• 15.Graham D. I., Lantos P. L.: Greenfield’s Neuropathology. Arnold, London 2002.
• 16.Griffiths I. R., Kyriakides E., Scott J.: Progressive axonopathy: an inherited neuropathy of boxer dogs. Quantitative and morphometric analysis of the peripheral nerve lesion. J. Neurol. Sci. 1986, 75, 69-88.
• 17.Griffiths I. R., Sharp N. J., McCulloch M. C.: Feline dysautonomia (The Key-Gaskell syndrome): an ultra structural study of autonomic ganglia and nerves. Neuropathol. Appl. Neurobiol. 1985, 11, 17-29.
• 18.Guscetti F., Pospischil A., Lauchli C., Ehrensperger F.: Pathomorphology of feline dysautonomia (Key-Gaskell syndrome). Histologic, electron microscopic and immunohistologic findings in 4 cats. Tieraerztl. Prax. K und G 1991, 19, 296-301.
• 19.Hahn C. N., Mayhew I. G., De Lahunta A.: Central neuropathology of equine grass sickness. Acta Neuropathol. 2001, 102, 153-159.
• 20.Higgins R. J., LeCouter R. A., Kornegay J. N., Coates J. R.: Late-onset progressive spinocerebellar degeneration in Brittany Spaniel dogs. Acta Neuropathol. 1998, 96, 97-101.
• 21.Inada S., Sakamoto H., Haruta K., Miyazono Y., Sasaki M., Yamauchi C., Igata A., Osame M., Fukunaga H.: A clinical study on hereditary progressive neurogenic muscularatrophy in Pointer dogs. Nippon Juigaku Zasshi 1978, 40, 539-547.
• 22.Jaggy A., Vandevelde M.: Multisystem neuronal degeneration in Cocker Spaniels. J. Vet. Intern. Med. 1988, 2, 117-120.
• 23.Montgomery D. L., Storts R. W.: Hereditary striatonigral and cerebello-olivary degeneration of the Kerry Blue Terrier. I. Gross and light microscopic central nervous lesions. Vet. Pathol. 1983, 20, 143-159.
• 24.Montgomery D. L., Storts R. W.: Hereditary striatonigral and cerebello -olivary degeneration of the Kerry Blue Terrier. II. Ultrastructural lesions in the caudate nucleus and cerebellar cortex. J. Neuropathol. Exp. Neurol. 1984, 43, 263-275.
• 25.Moreau P. M., Vallat J. M., Hugon J., Leboutet M. J., Vandevelde M.: Peripheral and central distal axonopathy of suspected inherited origin in Birman cats. Acta Neuropathol. 1991, 82, 143-146.
• 26.Palmer A. C., Medd R. K., Wilkinson G. T.: Spinal cord degeneration in hound ataxia. J. Small Anim. Pract. 1984, 25, 139-148.
• 27.Pumarola M., Fondevila D., Borra's D., Majo N., Ferrer I.: Neuronal vacuolation in young Rottweiler dogs. Acta Neuropathol. 1999, 97, 192-195.
• 28.Resibois A., Poncelet L.: Olivopontocerebellar atrophy (OPCA) in two adult cats, sporadic cases or new enetic entity. Vet. Pathol. 2004, 41, 20-29.
• 29.Tatalick L. M., Marks S. L., Baszler T. V.: Cerebellar abiotrophy characterized by granular cell loss in a Brittany. Vet. Pathol. 1993, 30, 385-388.
• 30.Toennissen J. G., Morin D. E.: Degenerative myelopathy. A comparative review. Compend. Contin. Edu. 1995, 17, 271-283.
• 31.Vite C. H., Dayrell-Hart B., Lexa F., Roy K., Van Winkle T., Steinberg S. A.: Atypical disease progression and MR imaging of a Kerry Blue Terrier with cerebellar cortical and extrapyramidal nuclear abiotrophy. Progr. Vet. Neurol. 1996, 7, 12-15.
• 32.Woodard J. C., Collins G. H., Hessler J. R.: Feline hereditary neuroaxonal dystrophy. Am. J. Pathol. 1974, 74, 551-566.