PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2012 | 56 | 4 |

Tytuł artykułu

Natural occurrence of thiouracil in urine of livestock in Poland

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Natural occurrence of thiouracil in bovine and swine urine in Poland was investigated. Under the national residue control programme, 537 urine samples were tested. In 77 samples (14.3%) thiouracil was detected above decision limit CCα (0.91 µg L⁻¹), including eight samples over the recommended concentration of 10 µg L⁻¹. Of the bovine urine samples, 95 and 99 percentiles have thiouracil concentration below 4.50 and 14.85 µg L⁻¹, and of porcine samples below 2.35 and 6.80 µg L⁻¹, respectively.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

56

Numer

4

Opis fizyczny

p.611-615,fig.,ref.

Twórcy

autor
  • Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
  • Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
  • Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
  • Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

Bibliografia

  • 1. Asea P.E., MacNeil J.D., Boison J.O.: An analytical method to screen for six thyreostatic drag residues in the thyroid gland and muscle tissues of food producing animals by liquid chromatography with absorption detection and liquid chromatography/mass spectrometry. J AOAC Int 2006, 89, 567-575.
  • 2. Batjoens P., De Brabander H.F., De Wasch K.: Rapid and high performance analysis of thyreostatic drug residues in urine using gas chromatography-mass spectrometry. J Chromatogr A 1996, 750, 127-132.
  • 3. Commission Decision 2009/152/EC, Off J Eur Commun 2009, L 54, 1.
  • 4. Council Directive 81/602/EC, Off J Eur Commun 1981, L 222, 32-33.
  • 5. Council Directive 96/23/EC, Off J Eur Commun 1996, L 125, 10.
  • 6. De Brabander H.F., Verbeke R.: Detection of antithyroid residues in meat and some organs of slaughtered animals. J Chromatogr 1975, 108, 141-151.
  • 7. European Food Safety Authority (EFSA). Report for 2009 on the results from the monitoring of veterinary medicinal product residues and other substances in live animals and animal products. 2009, Supporting publications 2011, 158, p. 70. Available from: www.efsa.europa.eu.
  • 8. European Union of Reference Laboratory (EURL). EURL guidance document: EURL'S view on state of art analytical methods for national residue control plans, 2007. Available from: www.rivm.nl/bibliotheek/digitaaldepot/crlguidance 2007.pdf.
  • 9. International Agency for Research on Cancer. Monographs on the Evaluation of Carcinogenic Risk to Humans. Some Thyrotropic Agents. IARC Lyon, France, 2001, vol. 79.
  • 10. Khvorostov A.: Fotoindukowane procesy przeniesienia protonu obserwowane w pochodnych tiouracylu. Thesis. Institute of Physics, Polish Academy of Sciences, Warszawa, 2006.
  • 11. Le Bizec B., Bichon E., Deceuninck Y., Prévost S., Monteau F., Antignac J.F., Dervilly-Pinel G.: Toward a criterion for suspect thiouracil administration in animal husbandry. Food Addit Contain 2011, 28, 840-847.
  • 12. Lõhmus M., Kallaste K., Le Bizec B.: Determination of thyreostats in urine and thyroid gland by ultra high performance liquid chromatography tandem mass spectrometry. J Chromatogr A 2009, 1216, 8080-8089.
  • 13. Pinel G., Bichon E., Pouponneau K., Maume D., Andre F., Le Bizec B.: Multi-residue method for the determination of thyreostats in urine samples using liquid chromatography coupled to tandem mass spectrometry after derivatisation with 3-iodobenzylbromide. J Chromatogr A 2005, 1085, 247-252.
  • 14. Pinel G., Mathieu S., Cesbron N., Maume D., De Brabander H.F., Andre F., Le Bizec B.: Evidence that urinary excretion of thiouracil in adult bovine submitted to a cruciferous diet can give erroneous indications of the possible illegal use of thyreostats in meat production. Food Addit Contain 2006, 23, 974-980.
  • 15. Vanden Bussche J., Vanhaecke L., Deceuninck Y., Verheyden K., Wille K., Bekaert K., Le- Bizec B., De Brabander H.F.: Development and validation of an ultrahigh performance liquid chromatography tandem mass spectrometry method for quantifying thyreostats in urine without derivatisation. J Chromatogr A 2010, 1217, 4285-4293.
  • 16. Vanden Bussche J., Vanhaecke L., Deceuninck Y., Wille K., Bekaert K., Le Bizec B., De Brabander H.F.: Ultrahigh performance liquid chromatography coupled to triple quadrupole mass spectrometry detection of natural occurring thiouracil in urine of untreated livestock, domesticated animals and humans. Food Addit Contam 2011, 28, 166-172.
  • 17. Wozniak B., Matraszek-Zuchowska I., Zmudzki J., Jedziniak P., Korycinska B., Sielska K., Witek S., Klopot A.: Liquid chromatography tandem mass spectrometry with ion trap and triple quadrupole analyzers for determination of thyreostatic drugs in urine and muscle tissue. Anal Chim Acta 2011, 700, 155-166.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-14b90eb3-efeb-4fcb-bf19-c1b80c39e96d
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.