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2019 | 28 | 4 |
Tytuł artykułu

How exposure to ultrafine and fine particles of car smoke can alter erythrocyte forms of male mice

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Języki publikacji
Exposure to particulate matter (PM) has been identified as being responsible for affecting human health. Their impacts on erythrocytes are still unclear, especially PMs emitted from motor vehicles. This study investigated the correlation between exposures to inflammatory agents of particulate matters (in terms of ultrafine particles, or PM0.1, and fine particles, or PM2.5) contained in gasoline engine carexhaust emissions and the deformation of mice erythrocytes. We used 65 male mice as experimental animals. The mice were exposed to the filtered and unfiltered PM0.1-PM2.5 for 100 seconds for as long as 8 consecutive days. The mice from each group were sacrificed on the 8th day of blood preparation. All blood samples were observed using a digital microscope (400x magnification) to calculate the amount of normal and deformed erythrocytes. The results showed that the increasing amount of PM0.1 and PM2.5 in the car smoke that was exposed to the mice caused the increasing of the erythrocyte deformation percentages. The erythrocyte deformation percentage was found linearly to the particle concentration.
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Opis fizyczny
  • Laboratory of Air Quality and Astro Imaging, Department of Physics, University of Brawijaya, Malang, East Java, Indonesia
  • Laboratory of Experimental Physics, Department of Physics, University of Brawijaya, Malang, East Java, Indonesia
  • Laboratory of Experimental Physics, Department of Physics, University of Brawijaya, Malang, East Java, Indonesia
  • 1. WARDOYO A.Y.P., SANTJOJO D.J.D.H., RAHAYUT., SUBAGYO S. Influence of smoking rate on ultrafine particle emission of cigarette smoke. Journal of Biological Researches. 23, 90, 2018.
  • 2. WARDOYO A.Y.P., MORAWSKA L., RISTOVSKI Z.D., MARSH J. Quantification of particle number and mass emission factors from combustion of Queensland trees. Environmental Science and Technology. 40, 5696, 2006.
  • 3. KARJALAINEN P., PIRJOLA L., HEIKKILÄ J., LÄHDE T., TZAMKIOZIS T., NTZIACHRISTOS L., KESKINEN J., RÖNKKÖ T. Exhaust particles of modern gasoline vehicles: A laboratory and an on-road study. Atmospheric Environment. 97, 262, 2014.
  • 4. KIM H., KANG K., KIM T. Measurement of particulate matter (PM2.5) and health risk assessment of cookinggenerated particles in the kitchen and living rooms of apartment houses. Sustainability. 10, 1, 2018.
  • 5. BETHA R., SELVAM V., BLAKE D.R., BALASUBRAMANIAN R. Emission characteristics of ultrafine particles and volatile organic compounds in a commercial printing center. Journal of the Air and Waste Management Association. 61, 1093, 2011.
  • 6. TEPE N., BAU M. Importance of nanoparticles and colloids from volcanic ash for riverine transport of trace elements to the ocean: Evidence from glacial-fed rivers after the 2010 eruption of Eyjafjallajökull Volcano, Iceland. Science of the Total Environment. 488-489, 243, 2014.
  • 7. LAZARIDIS M., LATOS M., ALEKSANDROPOULOU V., HOV O., PAPAYANNIS A., TØRSETH K. Contribution of forest fire emissions to atmospheric pollution in Greece. Air Quality, Atmosphere and Health. 1, 143, 2008.
  • 8. WARDOYO A.Y.P., MORAWSKA L., RISTOVSKI Z.D., JAMRISKA M., CARR S., JOHNSON G. Size distribution of particles emitted from grass fires in the Northern Territory, Australia. Atmospheric Environment. 41, 8609, 2007.
  • 9. XU Y., BARREGARD L., NIELSEN J., A. GUDMUNDSSON, WIERZBICKA A., AXMON A., JÖNSSON B.A.G., KÅREDAL M., ALBIN M. Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study. Particle and Fibre Toxicology. 10, 1, 2013.
  • 10. UPADHYAY S., GANGULY K., STOEGER T., SEMMLER-BHENKE M., TAKENAKA S., KREYLING W.G., PITZ M., REITMEIR P., PETERS A., EICKELBERG O., WICHMANN H.E. Cardiovascular and inflammatory effects of intratracheally instilled ambient dust from Augsburg, Germany, in spontaneously hypertensive rats (SHRs). Particle and Fibre Toxicology. 7, 1, 2010.
  • 11. HUK A., IZAK-NAU E., EL YAMANI N., UGGERUD H., VADSET M., ZASONSKA B., DUSCHL A., DUSINSKA M. Impact of nanosilver on various DNA lesions and HPRT gene mutations – effects of charge and surface coating. Particle and Fibre Toxicology. 12, 1, 2015.
  • 12. SCHNEIDER A., NEAS L.M., GRAFF D.W., HERBST M.C., CASCIO W.E., SCHMITT M.T., BUSE J.B., PETERS A., DEVLIN R.B. Association of cardiac and vascular changes with ambient PM2.5 in diabetic individuals. Particle and Fibre Toxicology. 7, 1, 2010.
  • 13. GEISER M., ROTHEN-RUTISHAUSER B., KAPP N., SCHÜRCH S., KREYLING W., SCHULZ H., SEMMLER M., HOF V.I., HEYDER J., GEHR P. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environmental Health Perspectives. 113, 1555, 2005.
  • 14. SOPPA V.J., SCHINS R.P.F., HENNIG F., NIEUWENHUIJSEN M.J., HELLACK B., QUASS U., KAMINSKI H., SASSE B., SHINNAWI S., KUHLBUSCH T.A.J., HOFFMANN B. Arterial blood pressure responses to short-term exposure to fine and ultrafine particles from indoor sources – A randomized sham-controlled exposure study of healthy volunteers. Environmental Research. 158, 225, 2017.
  • 15. JANTZEN K., MØLLER P., KAROTTKI D.G., OLSEN Y., BEKÖ G., CLAUSEN G., HERSOUG L.G., LOFT S. Exposure to ultrafine particles, intracellular production of reactive oxygen species in leukocytes and altered levels of endothelial progenitor cells. Toxicology. 359-360, 11, 2016.
  • 16. VLAANDEREN J.J, JANSSEN N.A., HOEK G., KESKI-RAHKONEN P., BARUPAL D.K., CASSEE F.R., GOSENS I., STRAK M., STEENHOF M., LAN Q., BRUNEKREEF B., SCALBERT A., VERMEULEN R.C.H. The impact of ambient air pollution on the human blood metabolome. Environmental Research. 156, 341, 2017.
  • 17. PRETORIUS E., MBOTWE S., BESTER J. Erythrocytes and their role as health indicator: Using structure in a patient-orientated precision medicine approach. Blood Reviews. 30, 263, 2016.
  • 18. FAES C., CHARRIN E., CONNES P., PIALOUX V., Martin C. Chronic physical activity limits blood rheology alterations in transgenic SAD mice. American Journal of Hematology. 90, E32, 2015.
  • 19. BELCHER J.D, MAHASETH H., WELCH T.E., OTTERBEIN L.E., HEBBEL R.P., VERCELLOTTI G.M. Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. The Journal of Clinical Investigation. 116, 808, 2006.
  • 20. CLARK M.R., MOHANDAS N., SHOHET S.B. Deformability of oxygenated irreversibly sickled cells. Journal of Clinical Investigation. 65, 189, 1980.
  • 21. CHARRIN E., OFORI-ACQUAH S.F., NADER E., SKINNER S., CONNES P., PIALOUX V., JOLY P., MARTIN C. Inflammatory and oxidative stress phenotypes in transgenic sickle cell mice. Blood Cells, Molecules, and Diseases. 62, 13, 2016.
  • 22. ZHANG Y., ZHANG W., WANG S., WANG C., XIE J., CHEN X., XU Y., MAO P. Detection of human erythrocytes influenced by iron deficiency anemia and thalassemia using atomic force microscopy. Micron. 43, 1287, 2012.
  • 23. WARDOYO A.Y.P., JUSWONO U.P., NOOR J.A.E. A study of the correlation between ultrafine particle emissions in motorcycle smoke and mice erythrocyte damages. Experimental and Toxicologic Pathology. 69, 649, 2017.
  • 24. QUIROS D.C., YOON S., DWYER H.A., COLLINS J.F., ZHU Y., HUAI T. Measuring particulate matter emissions during parked active diesel particulate filter regeneration of heavy-duty diesel trucks. Journal of Aerosol Science. 73, 48, 2014.
  • 25. MASKEY S., CHAE H., LEE K., DAN N.P., KHOI T.T., PARK K. Morphological and elemental properties of urban aerosols among PM events and different traffic systems. Journal of Hazardous Materials. 317, 108, 2016.
  • 26. WARDOYO A.Y.P., JUSWONO U.P., NOOR J.A.E. Measurements of PM2.5 motor emission concentrations and the lung damages from the exposure mice. In 2016 International Seminar on Sensors, Instrumentation, Measurement, and Metrology (ISSIMM). 2016.
  • 27. OLSEN Y., KAROTTKI D.G., JENSEN D.M., BEKÖ G., KJELDSEN B.U., CLAUSEN G., HERSOUG L., HOLST G.J., WIERZBICKA A., SIGSGAARD T., LINNEBERG A., MØLLER P., LOFT S. Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study. Environmental Health. 13, 1, 2014.
  • 28. ASGHARIAN B., MILLER F.J., PRICE O., SCHROETER J.D., EINSTEIN D.R., CORLEY R.A., BENTLEY T. Modeling particle deposition in the pig respiratory tract. Journal of Aerosol Science. 99, 107, 2016.
  • 29. FARAG M.R., ALAGAWANY M. Erythrocytes as a biological model for screening of xenobiotics toxicity. Chemico-Biological Interactions. 279, 73, 2018.
  • 30. THOMSON E.M., WILLIAMS A., YAUK C.L., VINCENT R. Toxicogenomic analysis of susceptibility to inhaled urban particulate matter in mice with chronic lung inflammation. Particle and Fibre Toxicology. 6, 1, 2009.
  • 31. JIMENEZ L.A., THOMPSON J., BROWN D.A., RAHMAN I., ANTONICELLI F., DUFFIN R., DROST E.M., HAY R.T., DONALDSON K., MACNEE W. Activation of NF-ĸB by PM10 occurs via an iron-mediated mechanism in the absence of IĸB degradation, Toxicology, and Applied Pharmacology. 166, 101, 2000.
  • 32. GYAWALI P., RICHARDS R.S., BWITITI P.T., NWOSE E.U. Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome. Blood Cells, Molecules, and Diseases. 54, 360, 2015.
  • 33. REDDY A.R.N., REDDY Y.N., KRISHNA D.R., HIMABINDU V. Multi wall carbon nanotubes induce oxidative stress and cytotoxicity in human embryonic kidney (HEK293) cells. Toxicology. 272, 11, 2010.
  • 34. GILLESPIE P.A., KANG G.S., ELDER A., GELEIN R., CHEN L., MOREIRA A.L., KOBERSTEIN J., TCHOUWONG K., GORDON T., CHEN L.C. Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: Short and long-term studies in mice. Nanotoxicology. 4, 106, 2010.
  • 35. PLUMMER L.E., CAROSINO C.M., BEIN K.J., ZHAO Y., WILLITS N., SMILEY-JEWELL S., WEXLER A.S., PINKERTON K.E. Pulmonary inflammatory effects of source-oriented particulate matter from California’s San Joaquin Valley. Atmospheric Environment. 119, 174, 2015.
  • 36. NEMMAR A., INUWA I.M. Diesel exhaust particles in blood trigger systemic and pulmonary morphological alterations. Toxicology Letters. 176, 20, 2008.
  • 37. FANG Z., JIANG C., TANG J., HE M., LIN X., CHEN X., HAN L., ZHANG Z., FENG Y., GUO Y., LI H., JIANG W. A comprehensive analysis of membrane and morphology of erythrocytes from patients with glucose-6-phosphate dehydrogenase deficiency. Journal of Structural Biology. 194, 235, 2016.
  • 38. PYRSHEV K.A., KLYMCHENKO A.S., CSÚCS G., DEMCHENKO A.P. Apoptosis, and eryptosis: Striking differences on biomembrane level. Biochimica et Biophysica Acta – Biomembranes. 1860, 1362, 2018.
  • 39. POMPEO G., GIRASOLE M., CRICENTI A., BOUMIS G., BELLELLI A., AMICONI S. Erythrocyte death in vitro induced by starvation in the absence of Ca2+.Biochimica et Biophysica Acta. 1798, 1047, 2010.
  • 40. PHAM C.T., KAMEDA T., TORIBA A., HAYAKAWA K. Polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in particulates emitted by motorcycles. Environmental Pollution. 183, 175, 2013.
  • 41. YAN C., ZHENG M., YANG Q., ZHANG Q., QIU X., ZHANG Y., FU H., LI X., ZHU T., ZHU Y. Commuter exposure to particulate matter and particle-bound PAHs in three transportation modes in Beijing, China. Environmental Pollution. 204, 199, 2015.
  • 42. WIERZBICKA A., NILSSON P.T., RISSLER J., SALLSTEN G., XU Y., PAGELS J.H., ALBIN M., ÖSTERBERG K., STRANDBERG B., ERIKSSON A., BOHGARD M., BERGEMALM-RYNELL K., GUDMUNDSSON A. Detailed diesel exhaust characteristics including particle surface area and lung deposited dose for better understanding of health effects in human chamber exposure studies. Atmospheric Environment. 86, 212, 2014.
  • 43. TONGO I., OGBEIDE O., EZEMONYE L. Human health risk assessment of polycyclic aromatic hydrocarbons (PAHs) in smoked fish species from markets in Southern Nigeria. Toxicology Reports. 4, 55, 2017.
  • 44. SARIGIANNIS D.A., KARAKITSIOS S.P., ZIKOPOULOS D., NIKOLAKI S., KERMENIDOU M. Lung cancer risk from PAHs emitted from biomass combustion. Environmental Research. 137, 147, 2015.
  • 45. BORTEY-SAM N., IKENAKA Y., AKOTO O., NAKAYAMA S.M.M, ASANTE K.A., BAIDOO E., OBIRIKORANG C., SAENGTIENCHAI A., ISODA N., NIMAKO C., MIZUKAWA H., ISHIZUKA M. Oxidative stress and respiratory symptoms due to human exposure to polycyclic aromatic hydrocarbons (PAHs) in Kumasi, Ghana. Environmental Pollution. 228, 311, 2017.
  • 46. LOUIS C., LIU Y., TASSEL P., PERRET P., CHAUMOND A., ANDRE M. PAH, BTEX, carbonyl compound, blackcarbon, NO2 and ultrafine particle dynamometer bench emissions for Euro 4 and Euro 5 diesel and gasolinepassenger cars. Atmospheric Environment. 141, 80, 2016.
  • 47. TSAI J., HUANG P., CHIANG H. Characteristics of volatile organic compounds from motorcycle exhaust emission during real-world driving. Atmospheric Environment. 99, 215, 2014.
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