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2012 | 59 | 1 |

Tytuł artykułu

Carotenoid-binding proteins; accessories to carotenoid function

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Understanding of the widespread biological importance of carotenoids is increasing. Accompanying this is the developing recognition that the interaction of carotenoids with other molecules, such as proteins, is also essential. Here the significance of carotenoid-protein interactions with respect to biological function is reviewed for three well characterised carotenoprotein complexes; crustacyanin, the orange carotenoid protein and glutathione-S-transferase P1. In addition a preliminary report is made on the recent partial purification of an echinenone-binding protein extracted from a New Zealand sea urchin, Evechinus chloroticus.

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  • Department of Biochemistry, University of Otago, Dunedin, New Zealand


  • Bernstein PS, Khachik F, Carvalho LS, Muir GJ, Zhao DY, Katz NB (2001) Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye. Exp Eye Res 72: 215-223. 
  • Bernstein PS, Zhao DY, Wintch SW, Ermakov IV, McClane RW, Gellermann W (2002) Resonance Raman measurement of macular carotenoids in normal subjects and in age-related macular degeneration patients. Ophthalmology 109: 1780-1787. 
  • Bhosale P, Larson AJ, Frederick JM, Southwick K, Thulin CD, Bernstein PS (2004) Identification and characterisation of a pi isoform of glutathione S-transferase as a zeaxanthin-binding protein in the macula of the human eye. J Biol Chem 279: 49447-49545. 
  • Britton G (1995) Structure and properties of carotenoids in relation to function. FASEB J 9: 1551-1558. 
  • Britton G, Liaaen-Jensen S, Pfander H, eds, (2004) Carotenoids Handbook. Birkhäuser Verlag, Basel.
  • Britton G (2008) Functions of intact carotenoids. In Carotenoids Vol.4 Natural Functions. Britton G, Liaaen-Jensen S, Pfander H, eds, pp 189-211. Birkhäuser Verlag, Basel.
  • Britton G, Halliwell JR (2008) Carotenoid-protein interactions. In Carotenoids Vol.4 Natural Functions. Britton G, Liaaen-Jensen S, Pfander H, eds, pp 99-118. Birkhäuser Verlag, Basel.
  • Buchwald M, Jencks WP (1968) Properties of the crustacyanins and the yellow lobster shell pigment. Biochemistry 7: 844-859. 
  • Chábera P, Durchan M, Shih PM, Kerfeld CA, Polívka T (2011) Excited-state properties of the 16 kDa red carotenoid protein from Arthrospira maxima. Biochim Biophys Acta 1807: 30-35. 
  • Cianci M, Rizkallah PJ, Olczak A, Raftery J, Chayen NE, Zagalsky PF, Helliwell JR (2001) Structure of lobster apocrustacyanin A1 using softer X-rays. Acta Crystallogr D Biol Crystallogr 57: 1219-1229. 
  • Cianci M, Rizkallah PJ, Olczak A, Raftery J, Chayen NE, Zagalsky PF, Helliwell JR (2002) The molecular basis of the colouration mechanism in lobster shell β-crustacyanin at 3.2-Å resolution. Proc Natl Acad Sci USA 99: 9795-9800. 
  • Czeczuga B, Czeczuga-Semeniuk E, Semeniuk A (2005) Carotenoids and carotenoproteins in Asellus aquaticus L. (Crustacea: Isopoda). Folia Biol (Krakow) 53: 109-114. 
  • Erdman JW, Bierer TL, Gugger ET (1993) Absorption and transport of carotenoids. Ann NY Acad Sci 691: 76-85. 
  • Flower DR (1996) The lipocalin protein family: structure and function. Biochem J 318: 1-14. 
  • Gilchrist BM, Lee WL (1972) Carotenoid pigments and their possible role in reproduction in the sand crab, Emerita analoga. Comp Biochem Physiol B 42: 263-294.
  • Griffiths M, Perrott P (1976) Seasonal changes in the carotenoids of the sea urchin Strongylocentrotus drobachiensis. Comp Biochem Physiol 55B: 435-441. 
  • Holt TK, Krogmann DW (1981) A carotenoid protein from cyanobacteria. Biochim Biophys Acta 637: 408-414.
  • Kerfeld CA, Sawaya MR, Brahmandam V, Cascio D, Ho KK, Trevithick-Sutton CC, Krogmann DW, Yeates TO (2003) The crystal structure of cyanobacterial water-soluble carotenoid-binding protein. Structure 11: 55-65. 
  • Okoh C, Mychkovsky I, Lakshman MR (1993) Isolation and some properties of a carotenoid-protein complex from rat liver. J Nutr Biochem 4: 569-575.
  • Polívka T, Kerfeld CA, Pascher T, Sundstrom V (2005) Spectroscopic properties of the carotenoid 3'-hydroxyechenone in the orange carotenoid protein from the cyanobacterium Arthrospira maxima. Biochemistry 44: 3994-4003. 
  • Rao KR (1985) Pigmentary effectors. In Integuments, pigments and hormonal processes. Bliss DE, Mantel LH, eds, pp 395-462. Academic Press, New York.
  • Rao MN, Ghosh P, Lakshman MR (1997) Purification and partial characterisation of a cellular carotenoid-binding protein from Ferret liver. J Biol Chem 272: 24455-24460. 
  • Symonds RC, Kelly MS, Caris-Veyrat C, Young AJ (2007) Carotenoids in the sea urchin Paracentrotus lividus: Occurrence of 9'-cis-echinenone as the dominant carotenoid in gonad colour determination. Comp Biochem Physiol B 148: 432-444. 
  • Symonds RC, Kelly MS, Suckling CC, Young AJ (2009) Carotenoids in the gonad and gut of the edible sea urchin Psammechinus miliaris. Aquaculture 288: 120-125.
  • Tsushima M, Matsuno T (1990) Comparative biochemical studies of carotenoids in sea urchins-I. Comp Biochem Physiol 96B: 801-810.
  • Velu CS, Czeczuga B, Munuswamy N (2003) Carotenoprotein complexes in entomostracan crustaceans (Streptocephalus dichotomus and Monina micrura). Comp Biochem Physiol B 135: 35-42. 
  • Wilson A, Ajlani G, Verbavatz JM, Vass I, Kerfeld CA, Kirilovsky D (2006) A soluble carotenoid protein involved in phycobilisome-related energy dissipation in cyanobacteria. Plant Cell 18: 992-1007. 
  • Wilson A, Punginelli C, Gall A, Bonetti C, Alexandre M, Routaboul JM, Kerfeld C, van Grondelle R, Robert B, Kennis JT, Kirilovsky D (2008) A photoactive carotenoid protein acting as a light intensity sensor. Proc Natl Acad Sci USA 105: 12075-12080. 
  • Zagalsky PF (1976) Carotenoid-protein complexes. Pure Appl Chem 47: 103-120.


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