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2016 | 65 | 2 |
Tytuł artykułu

Characterization of Staphylococcal Cassette Chromosome mec (SCCmec) in methicillin-resistant Staphylococcus epidermidis strains isolated from biomaterial-associated infections and their antibiotic

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Języki publikacji
This work aims to provide an insight into staphylococcal cassette chromosome mec elements and antibiotic resistance in clinical isolates of Staphylococcus epidermidis. The dominating type was SCCmec – IV. Fifteen isolates were assigned to SCCmec type III, two isolates to SCCmec type II. Most isolates were resistant to at least three of the non-β-lactam antibiotics tested. None of the strains exhibited resistance to new generation antibiotics, such as daptomycin and linezolid. Also, none of these strains showed resistance to tigecycline and only four strains were resistant to rifampin i.e. antibiotics which are very efficient in treating biofilm-associated infections.
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Opis fizyczny
  • Department of Microbiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland
  • Department of Microbiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland
  • Department of Microbiological and Laboratory Diagnostics, Bacteriological Laboratory, Regional Hospital in Poznan, Poznan, Poland
  • Barbier F., E. Ruppé, D. Hernandez, D. Lebeaux, P. Francois, B. Felix, A. Desprez, A. Maiga, P.L. Woerther, K. Gaillard and others. 2010. Methicillin-resistant coagulase-negative staphylococci in the community: high homology of SCCmec IVa between Staphylococcus epidermidis and major clones of methicillin-resistant Staphylococcus aureus. J. Infect. Dis. 202: 270–281.
  • Bloemendaal A.L., E.C. Brouwer and A.C. Fluit. 2010. Methicillin resistance transfer from Staphylocccus epidermidis to methicillin-susceptible Staphylococcus aureus in a patient during antibiotic therapy. PLoS One 5: e11841.
  • Bonilla H., M.D. Huband, J. Seidel, H. Schmidt, M. Lescoe, S.P. McCurdy, M.M. Lemmon, L.A. Brennan, A. Tait-Kamradt, L. Puzniak and others. 2010. Multicity outbreak of linezolid-resistant Staphylococcus epidermidis associated with clonal spread of a cfr-containing strain. Clin. Infect. Dis. 51: 796–800.
  • European Committee on Antimicrobial Susceptibility Testing (EUCAST). 2014. Breakpoint tables for interpretation of MICs and zone diameters Version 4.0., 2014.01.01.
  • Garza-Gonzalez E., D. Lopez, C. Pezina, W. Muruet, V. Bocanegra- Garcia, I. Munoz, C. Ramirez and J.M Llaca-Diaz. 2010a. Diversity of staphylococcal cassette chromosome mec structures in coagulase-negative staphylococci and relationship to drug resistance. J. Med. Microbiol. 59: 323–329.
  • Garza-Gonzalez E., R. Morfin-Otero, J.M. Llaca-Diaz and E. Rodriguez-Noriega. 2010b. Staphylococcal cassette chromosome mec (SCCmec) in methicillin-resistant coagulase-negative staphylococci. A review and the experience in a tertiary-care setting. Epidemiol. Infect. 138: 645–654.
  • Gu B., T. Kelesidis, S. Tsiodras, J. Hindler and R.M. Humphries. 2013. The emerging problem of linezolid-resistant Staphylococcus. J. Antimicrob. Chemother. 68: 4–11.
  • Hanssen A.M. and J.U. Ericson Sollid. 2006. SCCmec in staphylococci: genes on the move. FEMS Immunol. Med. Microbiol. 46: 8–20.
  • Hong T., X. Li, J. Wang, C. Sloan and C. Cicogna. 2007. Sequential linezolid-resistant Staphylococcus epidermidis isolates with G2576T mutation. J. Clin. Microbiol. 45: 3277–3280.
  • Ito T., Y. Katayama, K. Asada, N. Mori, K. Tsutsumimoto, C. Tiensasitorn and K. Hiramatsu. 2001. Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 45: 1323–1336.
  • Ito T., X.X. Ma, F. Takeuchi, K. Okuma, H. Yuzawa and K. Hiramatsu. 2004. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob. Agents Chemother. 48: 2637–2651.
  • International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG). 2009. Classification of Staphylococcal Cassette Chromosome mec (SCCmec). Guidelines for Reporting Novel SCCmec Elements. Antimicrob. Agents Chemother. 53: 4961–4967.
  • Li M., X. Wang, Q. Gao and Y. Lu. 2009. Molecular characterization of Staphylococcus epidermidis strains isolated from a teaching hospital in Shanghai, China. J. Med. Microbiol. 58: 456–461.
  • Ruppé E., F. Barbier, Y. Mesli, A. Maiga, R. Cojocaru, M. Benkhalfat, S. Benchouk, H. Hassaine, I. Maiga, A. Diallo and others. 2009. Diversity of staphylococcal cassette chromosome mec structures in methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus strains among outpatients from four countries. Antimicrob. Agents Chemother. 53: 442–449.
  • Schoenfelder S.M.K., K. Lange, M. Eckart, S. Hennig, S. Kozytska and W. Ziebuhr. 2010. Success through diversity – How Staphylococcus epidermidis establishes as a nosocomial pathogen. Int. J. Med. Microbiol. 300: 380–386.
  • Shore C. and D.C. Coleman. 2013. Staphylococcal cassette chromosome mec: recent advances and new insights. Int. J. Med. Microbiol. 303: 350–359.
  • Smyth D.S., A. Wong and D.A. Robinson. 2010. Cross-species spread of SCCmec IV sub-types in staphylococci. Infect. Genet. Evol. 11: 446–453.
  • Svensson K., B. Hellmark and B. Söderquist. 2011. Characterization of SCCmec elements in methicillin-resistant Staphylococcus epidermidis isolated from blood cultures from neonates during three decades. APMIS 119: 885–893.
  • Stewart P.S., W.M. Davison and J.N. Steenbergen. 2009. Daptomycin rapidly penetrates a Staphylococcus epidermidis biofilm. Antimicrob. Agents. Chemother. 53: 3505–3507.
  • Szczuka E. and A. Kaznowski. 2014. Antimicrobial activity of tigecycline alone or in combination with rifampin against Staphylococcus epidermidis in biofilm. Folia Microbiol. 59: 283–288.
  • Treviño M., L. Martínez-Lamas, P.A. Romero-Jung, J.M. Giráldez, J. Alvarez-Escudero and B.J. Regueiro. 2009. Endemic linezolid-resistant Staphylococcus epidermidis in a critical care unit. Eur. J. Clin. Microbiol. Infect. Dis. 28: 527–33.
  • Turlej A., W. Hryniewicz and J. Empel. 2011. Staphylococcal Cassette Chromosome mec (SCCmec) classification and typing methods: an Overview. Pol. J. Microbiol. 60: 95–103.
  • Wisplinghoff H., A.E. Rosato, M.C. Enright, M. Noto, W. Craig, and G.L. Archer. 2003. Related clones containing SCCmec type IV predominate among clinically significant Staphylococcus epidermidis isolates. Antimicrob. Agents Chemother. 47: 3574–3579.
  • Voung C. and M. Otto. 2002. Staphylococcus epidermidis infections. Microb. Infect. 4: 481–489.
  • Zhang K., J. McClure, S. Elsayed, T. Louie and J.M. Clony. 2005. Novel PCR Assay for characterization and concomitant subtyping of staphylococcal cassette chromosome mec Types I to V in Methicillin-Resistant Staphylococcus aureus. J. Clin. Microbiol. 43: 5026–5033.
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