Eksperymentalne metody wywoływania tętniaków aorty brzusznej ze szczególnym uwzględnieniem świni jako dużego modelu zwierzęcego

• Autorzy: Czerski A. , Bujok J. , Rusiecka A. , Zawadzki W. , Gnus J. , Hauser W. , Ratajczak K. , Witkiewicz W.

Warianty tytułu

EN

Experimental methods of abdominal aortic aneurysm creation with particular emphasis on swine as a large animal model

• Języki publikacji: PL

Abstrakty

PL

Tętniak aorty brzusznej (AAA) stanowi dziesiątą z kolei przyczynę śmierci wśród mężczyzn powyżej 55. roku życia. Metodą leczenia tętniaków o średnicy przewyż­szającej 5,5 cm jest zabieg operacyjny klasyczny lub wewnątrznaczyniowy. Odsetek zgo­nów i powikłań związanych z zabiegiem wciąż jest wysoki, co sprawia, że prowadzi się liczne badania nad etiopatogenezą, patofizjologią oraz leczeniem tętniaka aorty brzusznej. Opracowano liczne modele zwierzęce AAA. Do badań wykorzystuje się zwierzęta predys­ponowane oraz modele, u których tętniaka wywołuje się metodami chemicznymi lub fi­zycznymi. Świnie stanowią dobry model doświadczalny do udoskonalania nowych technik operacyjnych. Wykorzystuje się liczne metody fizyczne (szczególnie operacyjne) w celu wytworzenia tętniaka u świń oraz łączy się metody chemiczne z mechanicznymi, które stale są ulepszane.

EN

Abdominal aortic aneurysm (AAA) is on the 10th position of the causes of death in men above 55 years of age. Method of treatment of AAA measuring above 5,5 cm is the classical surgery or endovascular procedure. Death and complication rates associated with surgery are still high. For this reason further studies on pathogenesis, pathophysiology and treatment of abdominal aortic aneurysm are needed. Numerous animal models of AAA have been developed. Research is conducted on predisposed animals and on models, in which AAA have been induced by chemical or physical methods. Swine are good experi­mental model for the improvement of new surgical techniques. Many physical protocols are used to produce aneurysm in swine (especially operational), combinations of physical and chemical methods are also introduced and constantly improved.

• Wydawca: -
• Czasopismo: Acta Scientiarum Polonorum. Medicina Veterinaria
• Rocznik: 2011
• Tom: 10
• Numer: 4
• Opis fizyczny: s.5-22,fot.,tab.,bibliogr.

Twórcy

autor

Czerski A.

• Uniwersytet Przyrodniczy we Wrocławiu, Wrocław
• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Bujok J.

• Uniwersytet Przyrodniczy we Wrocławiu, Wrocław
• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Rusiecka A.

• Uniwersytet Przyrodniczy we Wrocławiu, Wrocław
• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Zawadzki W.

• Uniwersytet Przyrodniczy we Wrocławiu, Wrocław
• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Gnus J.

• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Hauser W.

• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Ratajczak K.

• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

autor

Witkiewicz W.

• WroVasc - Zintegrowane Centrum Medycyny Sercowo-Naczyniowej, Wojewódzki Szpital Specjalistyczny we Wrocławiu, Wrocław

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