Structure-activity relationship study for fungicidal activity of 1-(4-phenoxymethyl-2-phenyl-[1,3]dioxolan-2-ylmethyl)-1H-1,2,4-triazole derivatives against rice blast

• Autorzy: Hoshi T. , Yamada K. , Yoshizawa Y. , Oh K.
• Języki publikacji: EN

Abstrakty

EN

To explore new antifungal agents for rice blast control, the antifungal activity of a series of novel 1,2,4-triazole derivatives against Magnaporthe oryzae has been evaluated. The antifungal activity was determined by using in vitro mycelial growth inhibition tests. Among the 19 test compounds, we found that the compound 1-(4-phenoxymethyl-2-phenyl-[1,3]dioxolan-2-ylmethyl)-1H-1,2,4- triazole (Gj) displayed potent antifungal activity against M. oryzae. The IC50 value was found approximately 3.8±0.5 μM and the IC50 value of propiconazole was found to be approximately 3.7±0.2 μM, respectively. Structure-activity relationship studies on aromatic ring structures provided insight and information about the structural requirements for antifungal activity of this synthetic series against M. oryzae.

Słowa kluczowe

EN

antifungal agent; structure-activity relationship; fungicidal activity; fungicide; triazole derivative; rice; Oryza sativa; Magnaporthe oryzae; rice blast; plant disease

• Wydawca: -
• Czasopismo: Journal of Plant Protection Research
• Rocznik: 2015
• Tom: 55
• Numer: 4
• Opis fizyczny: p.383-388,fig.,ref.

Twórcy

autor

Hoshi T.

• Department of Biotechnology, Faculty of Bioresource Sciences, Akita Prefectural University, 241-438, Shimoshinjo Nakano, Akita 010-0195, Japan

autor

Yamada K.

• Department of Biotechnology, Faculty of Bioresource Sciences, Akita Prefectural University, 241-438, Shimoshinjo Nakano, Akita 010-0195, Japan

autor

Yoshizawa Y.

• Department of Biotechnology, Faculty of Bioresource Sciences, Akita Prefectural University, 241-438, Shimoshinjo Nakano, Akita 010-0195, Japan

autor

Oh K.

• Department of Biotechnology, Faculty of Bioresource Sciences, Akita Prefectural University, 241-438, Shimoshinjo Nakano, Akita 010-0195, Japan

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Identyfikatory

DOI

10.1515/jppr-2015-0051