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2014 | 61 | 2 |
Tytuł artykułu

Ex - translational function of tRNAs and their fragments in cancer

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
 Transfer RNA (tRNA) molecules are most commonly known as the molecular amino acids carriers and also because of the role they play in a protein biosynthesis process. However, tRNA biology has revealed stupendous levels of many unexpected discoveries that put a new light on tRNA function in different processes besides translation, like apoptosis or cancer development. In recent years various species of RNAs have been found differentially expressed in different types of cancer. In this review we focus our attention on tRNAs as well as on tRNA-derived small RNAs ex-translational functions in human cells in oncogenesis and oncobiology.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
61
Numer
2
Opis fizyczny
p.211-216,ref.
Twórcy
  • Institute of Bioorganic Chemistry Polish Academy of Sciences, Poznan, Poland
  • Institute of Bioorganic Chemistry Polish Academy of Sciences, Poznan, Poland
  • Institute of Bioorganic Chemistry Polish Academy of Sciences, Poznan, Poland
Bibliografia
  • Abelson J, Trotta CR, Li H (1998) tRNA splicing. J Biol Chem 273: 12685-12688. 
  • Akashi H (1994) Synonymous codon usage in Drosophila melanogaster: Natural selection and translational accuracy. Genetics 136: 927-935. 
  • Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T (2003) The small RNA profile during Drosophila melanogaster development Dev Cell 5: 337-350. 
  • Borek E, Baliga BS, Gehrke CW, Kuo CW, Belman S, Troll W, Waalkes TP (1977) High turnover rate of transfer RNA in tumor tissue. Cancer Res 37: 3362-3366. 
  • Cairns RA, Harris IS, Mak TW (2011) Regulation of cancer cell metabolism. Nat Rev Cancer 11: 85-95. 
  • Ceballos M, Vioque A (2007) tRNase Z. Protein Pept Lett 14: 137-145. 
  • Eis PS, Tam W, Sun L, Chadburn A, Li Z, Gomez MF, Lund E, Dahlberg JE (2005) Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 102: 3627-3632. 
  • Dinger ME, Mercer TR, Mattick JS (2008) RNAs as extracellular signaling molecules. J Mol Endocrinol 40: 151-159. 
  • Dittmar KA, Goodenbour JM, Pan T (2006) Tissue-specific differences in human transfer RNA expression. PLoS Genet 2: e221. 
  • Dong J, Qiu H, Garcia-Barrio M, Anderson J, Hinnebusch AG (2000) Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain. Mol Cell 6: 269-279. 
  • Dorner S, Polacek N, Schulmeister U, Panuschka C, Barta A (2002) Molecular aspects of the ribosomal peptidyl transferase. Biochem Soc Trans 30: 1131-1136. 
  • Durdevic Z, Schaefer M (2013) tRNA modifications: necessary for correct tRNA-derived fragments during the recovery from stress? Bioessays 35: 323-327. 
  • Frank DN, Pace NR (1998) Ribonuclease P: unity and diversity in a tRNA processing ribozyme. Annu Rev Biochem 67: 153-180. 
  • Gebetsberger J, Zywicki M, Künzi A, Polacek N (2012) tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii. Archaea 2012: 260909. 
  • Giegé R (2008) Toward a more complete view of tRNA biology. Nat Struct Mol Biol 15: 1007-1014. 
  • Gillies RJ, Robey I, Gatenby RA (2008) Causes and consequences of increased glucose metabolism of cancers. J Nucl Med 49 (Suppl 2): 24S-42S. 
  • Hao S, Sharp JW, Ross-Inta CM, McDaniel BJ, Anthony TG, Wek RC, Cavener DR, McGrath BC, Rudell JB, Koehnle TJ, Gietzen DW (2005) Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex. Science 307: 1776-1778. 
  • Hauptman N, Glavac D (2013) MicroRNAs and long non-coding RNAs: prospects in diagnostics and therapy of cancer. Radiol Oncol 47: 311-318. 
  • Haussecker D, Huang Y, Lau A, Parameswaran P, Fire AZ, Kay MA (2010) Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA 16: 673-695. 
  • Hopper AK, Shaheen HH (2008) A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Trends Cell Biol 18: 98-104. 
  • Ivanov P, Emara MM, Villen J, Gygi SP, Anderson P (2011) Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell 43: 613-623. 
  • Jones RG, Thompson CB (2009) Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev 23: 537-548. 
  • Jöchl C, Rederstorff M, Hertel J, Stadler PF, Hofacker IL, Schrettl M, Haas H, Hüttenhofer A (2008) Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis. Nucleic Acids Res 36: 2677-2689. 
  • Kawaji H, Nakamura M, Takahashi Y, Sandelin A, Katayama S, Fukuda S, Daub CO, Kai C, Kawai J, Yasuda J, Carninci P, Hayashizaki Y (2008) Hidden layers of human small RNAs. BMC Genomics 9: 157. 
  • Kawamura Y, Saito K, Kin T, Ono Y, Asai K, Sunohara T, Okada TN, Siomi MC, Siomi H (2008) Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 453: 793-797. 
  • Kuchino Y, Borek E (1978) Tumour-specific phenylalanine tRNA contains two supernumerary methylated bases. Nature 271: 126-129. 
  • Kuchino Y, Borek E, Grunberger D, Mushinski JF, Nishimura S (1982) Changes of post-tanscriptional modification of wye base in tumor-specific tRNAPhe. Nucleic Acids Res 10: 6421-6432. 
  • Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE (2006) Characterization of the piRNA complex from rat testes. Science 313: 363-367. 
  • Lee YS, Shibata Y, Malhotra A, Dutta A (2009) A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes Dev 23: 2639-2649. 
  • Li Z, Ender C, Meister G, Moore PS, Chang Y, John B (2012) Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res 40: 6787-6799. 
  • Loeb LA, Loeb KR, Anderson JP (2003) Multiple mutations and cancer. Proc Natl Acad Sci USA 100: 776-781. 
  • Loftfield RB, Vanderjagt D (1972) The frequency of errors in protein biosynthesis. Biochem J 128: 1353-1356. 
  • Lui WO, Pourmand N, Patterson BK, Fire A (2007) Patterns of known and novel small RNAs in human cervical cancer. Cancer Res 67: 6031-6043. 
  • Mahlab S, Tuller T, Linial M (2012) Conservation of the relative tRNA composition in healthy and cancerous tissues. RNA 18: 640-652. 
  • Martens-Uzunova ES, Jalava SE, Dits NF, van Leenders GJ, Møller S, Trapman J, Bangma CH, Litman T, Visakorpi T, Jenster G (2012) Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer. Oncogene 31: 978-991. 
  • Maute RL, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, Dalla-Favera R (2013) tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma. Proc Natl Acad Sci USA 110: 1404-1409. 
  • Mei Y, Yong J, Liu H, Shi Y, Meinkoth J, Dreyfuss G, Yang X (2010) tRNA binds to cytochrome c and inhibits caspase activation. Mol Cell 37: 668-678. 
  • Melnyk CW, Molnar A, Baulcombe DC (2011) Intercellular and systemic movement of RNA silencing signals. EMBO J 30: 3553-3563. 
  • Metzler M, Wilda M, Busch K, Viehmann S, Borkhardt A (2004) High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 39: 167-169. 
  • Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ (2003) Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 1: 882-889. 
  • Nawrot B, Sochacka E, Düchler M (2011) tRNA structural and functional changes induced by oxidative stress. Cell Mol Life Sci 68: 4023-4032. 
  • Noerholm M, Balaj L, Limperg T, Salehi A, Zhu LD, Hochberg FH, Breakefield XO, Carter BS, Skog J (2012) RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. BMC Cancer 12: 22. 
  • Pavon-Eternod M, Gomes S, Rosner MR, Pan T (2013) Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. RNA 19: 461-466. 
  • Pavon-Eternod M, Gomes S, Geslain R, Rosner MR, Pan T (2009) tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Res 37: 7268-7280. 
  • Sana J, Faltejskova P, Svoboda M, Slaby O (2012) Novel classes of non-coding RNAs and cancer. J Transl Med 10: 103. 
  • Sobala A, Hutvagner G (2011) Transfer RNA-derived fragments: origins, processing, and functions. Wiley Interdiscip Rev RNA 2: 853-862. 
  • Sobala A, Hutvagner G (2013) Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells. RNA Biol 10: 553-563. 
  • Speer J, Gehrke CW, Kuo KC, Waalkes TP, Borek E (1979) tRNA breakdown products as markers for cancer. Cancer 44: 2120-2123. 
  • Solomon SJ, Fischbein A, Sharma K, Borek E (1985) Modified nucleosides in asbestos workers at high risk of malignant disease: results of a preliminary study applying discriminant analysis. Br J Ind Med 42: 560-562. 
  • Sung J, Turner J, McCarthy S, Enkemann S, Li CG, Yan P, Huang T, Yeatman TJ (2004) Oncogene regulation of tumor suppressor genes in tumorigenesis. Carcinogenesis 26: 487-494. 
  • Tavtigian SV, Simard J, Teng DH, Abtin V, Baumgard M, Beck A, Camp NJ, Carillo AR, Chen Y, Dayananth P, Desrochers M, Dumont M, Farnham JM, Frank D, Frye C, Ghaffari S, Gupte JS, Hu R, Iliev D, Janecki T, Kort EN, Laity KE, Leavitt A, Leblanc G, McArthur-Morrison J, Pederson A, Penn B, Peterson KT, Reid JE, Richards S, Schroeder M, Smith R, Snyder SC, Swedlund B, Swensen J, Thomas A, Tranchant M, Woodland AM, Labrie F, Skolnick MH, Neuhausen S, Rommens J, Cannon-Albright LA (2001) A candidate prostate cancer susceptibility gene at chromosome 17p. Nat Genet 27: 172-180. 
  • Tsui NB, Ng EK, Lo YM (2006) Molecular analysis of circulating RNA in plasma. Methods Mol Biol 336: 123-134. 
  • Waalkes TP, Gehrke CW, Tormey DC, Zumwalt RW, Hueser JN, Kuo KC, Lakings DB, Ahmann DL, Moertel CG (1975) Urinary excretion of polyamines by patients with advanced malignancy. Cancer Chemother Rep 59: 1103-1116. 
  • Węgrzyn G, Węgrzyn A (2008) Is tRNA only a translation factor or also a regulator of other processes? J Appl Genet 49: 115-122. 
  • Williamson D, Lu YJ, Fang C, Pritchard-Jones K, Shipley J (2006) Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma. Genes Chromosomes Cancer 45: 839-845. 
  • White RJ (2005) RNA polymerases I and III growth control and cancer. Nat Rev Mol Cell Biol 6: 69-78. 
  • Yamasaki S, Ivanov P, Hu GF, Anderson P (2009) Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol 185: 35-42. 
  • Yoda M, Kawamata T, Paroo Z, Ye X, Iwasaki S, Liu Q, Tomari Y (2010) ATP-dependent human RISC assembly pathways. Nat Struct Mol Biol 17: 17-23. 
  • Zhang S, Sun L, Kragler F (2009) The phloem-delivered RNA pool contains small noncoding RNAs and interferes with translation. Plant Physiol 150: 378-387. 
  • Zhao H, Bojanowski K, Ingber DE, Panigrahy D, Pepper MS, Montesano R, Shing Y (1999) New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: inhibition of endothelial cell growth. J Cell Biochem 76: 109-117. 
  • Zhou DH, Lee J, Frankenberger C, Geslain R, Rosner M, Pan T (2012) Anti-tumor effects of an engineered "killer" transfer RNA. Biochem Biophys Res Commun 427: 148-153. 
  • Zhou T, Weems M, Wilke CO (2009) Translationally optimal codons associate with structurally sensitive proteins. Mol Biol Evol 26: 1571-1580. 
  • Zhou Y, Goodenbour JM, Godley LA, Wickrema A, Pan T (2009) High levels of tRNA abundance and alteration of tRNA chargning bybortezomib in multiple myeloma. Biochem Biophys Res Commun 385: 160-164. 
  • Zywicki M, Bakowska-Zywicka K, Polacek N (2012) Revealing stable processing products from ribosome-associated small RNAs by deep-sequencing data analysis. Nucleic Acids Res 40: 4013-4024. 
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Bibliografia
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