In studies took into account 50 mothers and 229 puppies of silver fox as well as 45 mothers and 326 puppies of polar fox. The animals were allocated to 5 group depending on method of separation puppies from their mothers. Puppies from 1-3 groups were in pernament contact with mothers by sight, smell and hearing. The puppies from 1 and 4 groups were in maternal cages, the puppies from others groups were mooved far-off part of farm. Observations of animals behaviour /on 2 mother and their puppies from every group/ were made in weaning day and in two next days. The method of litter weaning effected the animals behaviour during and after the weaning, as well as their body weight, exterior and cover quality. The mother of polar fox the most responded to weaning of puppies. The every puppies of silver fox demonstrated clear yearning and anxiety.