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2013 | 60 | 3 |
Tytuł artykułu

Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Background & Aims: Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption. Methods: The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects 13C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution. Results: In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% <30.1-43.3%>). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% <23.1-37.2%>). Results of six tests with GTE were abnormal. Conclusions: Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.
Wydawca
-
Rocznik
Tom
60
Numer
3
Opis fizyczny
p.481-483,ref.
Twórcy
autor
  • Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland
  • Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland
autor
  • Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland
  • Department of Internal Diseases, Metabolism and Dietetics, Poznan University of Medical Sciences, Poznan, Poland
autor
  • Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland
  • Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland
autor
  • Department of Neonatology, Poznan University of Medical Sciences, Poznan, Poland
  • Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland
  • Department of Internal Diseases, Metabolism and Dietetics, Poznan University of Medical Sciences, Poznan, Poland
Bibliografia
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  • Collins QF, Liu HY, Pi J, Liu Z, Quon MJ, Cao W (2007) Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase. J Biol Chem 282: 30143-30149.  
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  • Kim J, Koo SI, Noh SK (2012) Green tea extract markedly lowers the lymphatic absorption and increases the biliary secretion of 14C-benzo[a]pyrene in rats. J Nutr Biochem 23: 1007-1711.  
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  • Lee MS, Kim CT, Kim IH, Kim Y. (2009) Inhibitory effects of green tea catechin on the lipid accumulation in 3T3-L1 adipocytes. Phytother Res 23: 1088-1091.  
  • Lee MS, Kim CT, Kim Y (2009) Green tea (-)-epigallocatechin-3-gallate reduces body weight with regulation of multiple genes expression in adipose tissue of diet-induced obese mice. Ann Nutr Metab 54: 151-157.  
  • Lisowska A, Pogorzelski A, Oracz G, Siuda K, Skorupa W, Rachel M, Cofta S, Piorunek T, Walkowiak J (2011) Oral antibiotic therapy improves fat absorption in cystic fibrosis patients with small intestine bacterial overgrowth. J Cyst Fibros10: 418-421. 
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  • Shrestha S, Ehlers S J, Lee JY, Fernandez ML, Koo SI (2009) Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein 1-c mRNA and its responsive genes in fructose-fed, ovariectomized rats. J Nutr 139: 640-645. 
  • Tanaka K, Tamaru S, Nishizono S, Miyata Y, Tamaya K, Matsui T, Tanaka T, Echizen Y, Ikeda I. (2010) Hypotriacylglycerolemic and antiobesity properties of a new fermented tea product obtained by tea-rolling processing of third-cropp green tea (Camellia sinensis) leaves and loquat (Eriobotrya japonica) leaves. Biosci Biotechnol Biochem 74: 1606-1612.  
  • Unno T, Tago M, Suzuki Y, Nozawa A, Sagesaka YM, Kakuda T, Egawa K, Kondo K (2005) Effect of tea catechins on postprandial plasma lipid responses in human subjects. Br J Nutr 93: 543-547.  
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-07853c10-57e1-45bd-ad2b-08968ac58b85
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