Putative shared mechanisms in autism spectrum disorders and attention deficit hyperactivity disorder, a systematic review of the role of oxidative stress

• Autorzy: Sa-Carneiro F. , Calhau C. , Coelho R. , Figueiredo-Braga M.
• Języki publikacji: EN

Abstrakty

EN

Oxidative stress is now believed to play a crucial role for neurodevelopment disorders such as autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD). To review the most recent literature regarding the role of oxidative stress for the pathophysiology of ASD and ADHD, we conducted a systematic search of the relevant literature and further discuss the clinical and research implications of this knowledge. A systematic search in PubMed database retrieved 132 articles, of which 33 were included in the review. This review found relevant evidence concerning the role of oxidative status in ASD and ADHD, albeit with some contradictory findings. In order to overcome the incongruities found, more studies are needed in the study of neurodevelopmental disorders, with more thorough study designs and particular attention to the accuracy of the diagnostic tools used for the cases included.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2020
• Tom: 80
• Numer: 2
• Opis fizyczny: p.129-138,fig.,ref.

Twórcy

autor

Sa-Carneiro F.

• Department of Neurosciences and Mental Health, Faculty of Medicine, University of Porto, Porto, Portugal
• Psychiatry and Mental Health Clinic, Centro Hospitalar Sao Joao, Porto, Portugal
• I3S‑Instituto de Inovacao e Investigacao em Saude, Porto, Portugal

autor

Calhau C.

• Center for Health Technology and Services Research (CINTESIS), Porto, Portugal,
• Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciencias Medicas, Universidade Nova de Lisboa, Lisbon, Portugal

autor

Coelho R.

• Department of Neurosciences and Mental Health, Faculty of Medicine, University of Porto, Porto, Portugal
• Psychiatry and Mental Health Clinic, Centro Hospitalar Sao Joao, Porto, Portugal

autor

Figueiredo-Braga M.

• Department of Neurosciences and Mental Health, Faculty of Medicine, University of Porto, Porto, Portugal
• I3S‑Instituto de Inovacao e Investigacao em Saúde, Porto, Portugal
• Medical Psychology Unit, Department of Clinical Neurosciences and Mental Health Faculty of Medicine, University of Porto, Porto, Portugal

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Identyfikatory

DOI

10.21307/ane-2020-013