Semispecific TPPII inhibitor Ala-Ala-Phe-chloromethylketone (AAF-cmk) displays cytotoxic activity by induction of apoptosis, autophagy and protein aggregation in U937 cells

• Autorzy: Bialy L.P. , Fayet J. , Wilczynski G.M. , Mlynarczuk-Bialy I.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

proteolysis; ubiquitin-proteasome system; tripeptidyl peptidase II; anticancer strategy; proteasome inhibitor; U937 cell; protein aggregation; apoptosis; autophagy; transmission electron microscopy

• Wydawca: -
• Czasopismo: Folia Histochemica et Cytobiologica
• Rocznik: 2018
• Tom: 56
• Numer: 4
• Opis fizyczny: p.185-194,fig.,ref.

Twórcy

autor

Bialy L.P.

• Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, Chalubinskiego 5, 02–004 Warsaw, Poland

autor

Fayet J.

• Department of Ophthalmology, First Medical Faculty, Medical University of Warsaw, Warsaw, Poland

autor

Wilczynski G.M.

• Laboratory of Molecular and Systemic Neuromorphology, Department of Neurophysiology, Nencki Institute of Experimental Biology, PAN, Warsaw, Poland

autor

Mlynarczuk-Bialy I.

• Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, Warsaw, Poland

Identyfikatory

DOI

10.5603/FHC.a2018.0020