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2010 | 70 | 1 |
Tytuł artykułu

The functional effect of epigallocatechin gallate on ischemic stroke in rats

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
We evaluated the efficacy of epigallocatechin gallate (EGCG) for improving function in rats with transient middle cerebral artery occlusion (MCAO). Three procedures underwent for each groups; MCAO and EGCG treatment, MCAO without treatment (MCAO control), and sham operation. Function was evaluated on days 1, 5, 10, and 14 after ischemia, using a modified sticky-tape test and the percentage weight borne on the paretic leg. Infarct volume did not differ between the EGCG-treated and MCAO control groups. Compared with the MCAO control group, the EGCG-treated group showed improved forelimb function and had normal function by day 10 (P<0.05). The improvements persisted until day 14 post-ischemia. In contrast, hind limb function did not differ between the EGCG-treated and MCAO control groups. Thus, EGCG improved certain aspects of function of forelimb until day 14 after MCAO in rats.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
70
Numer
1
Opis fizyczny
p.40-46,fig.,ref.
Twórcy
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Center for Biomedical Informatics, Harvard Medical School, Boston, MA, USA
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
autor
  • Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Bibliografia
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