Horizontal transfer and functional evaluation of high pathogenicity islands in Avian Escherichia coli

• Autorzy: Tu J. , Qi K. , Song X. , Xue T. , Ji H. , Shao Y. , Liu H. , Zhou X. , Zhu L.
• Języki publikacji: EN

Abstrakty

EN

High pathogenicity islands (HPIs) in Escherichia coli encode genes that are primarily involved in iron uptake and regulation, and confer virulence and pathogenicity. The aim of this study was to investigate the transfer of HPIs in avian E. coli and identify the function of HPI in the acceptor strain. The HPI transfer strain was obtained under conditions of low temperature and low iron abundance, and the donor and acceptor strains were confirmed. E. coli HPIs are transferred by horizontal gene transfer events, which are likely mediated primarily by homologous recombination in HPI-adjacent sequences. Assays for biological activity and pathogenicity changes in the acceptor strain indicated that HPIs might not be involved in pathogenesis in avian E. coli, and thus the main function of HPIs in this strain of bacteria may be to regulate iron nutrition.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2017
• Tom: 20
• Numer: 2
• Opis fizyczny: p.395-402,fig.,ref.

Twórcy

autor

Tu J.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Qi K.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Song X.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Xue T.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Ji H.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Shao Y.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Liu H.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Zhou X.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

autor

Zhu L.

• College of Animal Science and Technology, Anhui Agriculture University, Hefei, Anhui 230036, China
• Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei, Anhui 230036, China

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Identyfikatory

DOI

10.1515/pjvs-2017-0048