Physical stress for overproduction of biomass and flavonoids in cell suspension cultures of Boesenbergia rotunda

• Autorzy: Yusuf N A , Annuar M. S. M. , Khalid N.
• Języki publikacji: EN

Abstrakty

EN

Flavonoid, a bioactive compound isolated from the rhizomes of Boesenbergia rotunda, exhibited antibiotic and anti-inflammatory properties and has also shown high inhibitory activity of dengue-2 virus protease. Several factors are responsible for the production of flavonoid in cell cultures. In the present study, the effects of initial inoculation volume, temperature and speed of agitation on cell growth, total and selected flavonoid in suspension cultures of B. rotunda were determined. High performance liquid chromatography analysis showed that a 2 % inoculation volume induced a significantly high accumulation of biomass and of flavonoid in the cells. The cells cultured at 25 ºC showed significantly high biomass and selected flavonoid accumulation while differences in medium agitation significantly affected the yield of selected flavonoid.

• Wydawca: -
• Czasopismo: Acta Physiologiae Plantarum
• Rocznik: 2013
• Tom: 35
• Numer: 05
• Opis fizyczny: p.1713-1719,fig.,ref.

Twórcy

autor

Yusuf N A

• Centre of Biotechnology for Agriculture Research, Biotechnology and Bioproduct Research Cluster, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
• Faculty of Plantation and Agrotechnology, University of Technology MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia 123

autor

Annuar M. S. M.

• Centre of Biotechnology for Agriculture Research, Biotechnology and Bioproduct Research Cluster, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

autor

Khalid N.

• Centre of Biotechnology for Agriculture Research, Biotechnology and Bioproduct Research Cluster, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

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