Effects of tadalafil (PDE5 inhibitor) and roflumilast (PGE4 inhibitor) on airway reactivity and markers of inflammation in ovalbumin-induced airway hyperresponsiveness in guinea pigs

• Autorzy: Mokry J. , Urbanova A. , Medvedova I. , Kertys M. , Mikolka P. , Kosutova P. , Mokra D.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

phosphodiesterase; chronic obstructive pulmonary disease; airway reactivity; eosinophil; bronchial asthma; pulmonary hypertension; smooth muscle; inflammation; dexamethasone; roflumilast; tadalafil; guinea pig

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology
• Rocznik: 2017
• Tom: 68
• Numer: 5
• Opis fizyczny: p.721-730,fig.,ref.

Twórcy

autor

Mokry J.

• Biomedical Center Martin and Department of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 4C Mala Hora Street, 03601 Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Urbanova A.

• Department of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Medvedova I.

• Department of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Kertys M.

• Department of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Mikolka P.

• Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Kosutova P.

• Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia

autor

Mokra D.

• Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
• Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia