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2015 | 74 | 3 |

Tytuł artykułu

Histology and ultrastructure of the uterus of African giant rat (Cricetomys Gambianus, Waterhouse) during oestrous cycle

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This study describes histology and ultrastructure of uterus in the African giant rat during oestrous cycle. Endometrial histology displayed glandular mucosa consisting of lamina epithelialis and lamina propria mucosae. Its epithelium varied between simple and pseudostratified columnar. The myometrium consisted of inner circular and outer longitudinal smooth muscles with medium sized arteries and veins in-between. The perimetrium contained simple squamous epithelium. Endometrial ultrastructures were variable during oestrous cycle. At mid oestrus, hemidesmosomes anchored undulating basement membrane of the mucosal epithelium. Preponderance spherical mitochondria, lipofuscin granules concentration, flocculent homogenous materials and indented nuclei were displayed. At mid metoestrus, late metoestrus/early dioestrus and mid dioestrus, the base of the mucosal columnar epithelium lain on relatively straight basement membrane and their cytoplasmic ultrastructure displayed variation to mid oestrus. Epithelial apex showed intermediate filament, microvilli and junctional complexes. The uterine glands occurred in variable numbers and sizes during oestrous cycle and shared similar ultrastructure. Mid dioestrus showed cell ultrastructure of uterine glands having apical accumulation of secretory vesicles. Some actively secreting uterine glands were lined by simple ciliated columnar epithelium mingled with pseudostratified epithelium. The findings of the study indicate that giant rat endometrial ultrastructure varies during oestrous cycle and glandular secretion is merocrine. (Folia Morphol 2015; 74, 3: 311–317)

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  • Department of Veterinary Anatomy, Federal University of Agriculture, Abeokuta, Nigeria
  • Department of Veterinary Anatomy, University of Ibadan, Ibadan, Nigeria


  • 1. Akinloye AK, Abatan MO, Alaka OO, Oke BO (2001) Histo-mophometric and histopathological studies on the effect of calotropis procera (Giant milk weed) on the male reproductive organs of Wistar rats. Afr J Biomed Res, 4: 55–59.
  • 2. Akinloye AK, Oke BO (2009) The uterus of the female African giant rat (Cricetomys gambianus Waterhouse) at Different stages of the oestrous cycle; gross morphometry. Nigerian Vet J, 30: 1–7.
  • 3. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD (1989) Energy conversion: mitochondria and chloroplasts. In: Molecular biology of the cell. Garland Publishing, Inc. New York, pp. 341–404.
  • 4. Corbeil LB, Chatterjee A, Foresman L, Westfall JA (1985) Ultrastructure of cyclicchanges in the murine uterus, cervix, and vagina. Tissue Cell, 17: 53–68.
  • 5. Eurell JA, Frappier BL (2006) Female reproductive system. In: Dellmann’s textbook of veterinary histology. 6th Ed. Blackwell Publishing, Ames, IA, pp. 256–278.
  • 6. Fawcett DW, Jensh RP (2002) Female reproductive system. In: Bloom and Fawcett’s concise histology. 2nd Ed. Arnold Publishers, London, pp. 283–296.
  • 7. Hafez ESE (1987) Reproductive cycles. In: Hafez ESE ed. Reproduction in farm animals. 5th Ed. Lea and Febiger, Philadelphia, pp. 107–129.
  • 8. Knight M (1988) Thermoregulation in the largest African cricetid, the giant rat Cricetomys gambianus. Comparative Bioch Physiol A Physiol, 89: 705–708.
  • 9. Madekurozwa MC, Oke BO, Akinloye AK (2009) Immunohistochemical localization of the progesterone and oestrogen alpha receptors in the uterine horns of the African giant rat (Cricetomys gambianus). Anat Histol Embryol, 38: 419–423.
  • 10. Malekani M, Paulus J (1989) Quelques aspects de la consommation du cricétome, Cricetomys (Rongeurs), par des populations zaïroises. Tropicultura, 7: 141–144.
  • 11. Oke OA, Oke BO (1999) Vaginal cytological changes during the oestrous cycle of the adult female African giant (C. gambianus, Waterhouse). Tropical Vet, 17: 169–180.
  • 12. Skinner JD, Smithers RHN (1990) The mammals of the Southern African subregion. University of Pretoria.
  • 13. Weiss L (1983) The female reproductive system. In: Histology, cell and tissue biology. 5th Ed. Elsevier Science Publishing Co., Inc., New York, pp. 914–943.

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